Hydrostatic Pressure Generator (HPG)

Hydrostatic Pressure Generator Device (U.S. Pat. No. 9,303,244)

Methods and device of using hydrostatic pressure in a process(Pat. Pend.)

Hydrostatic Pressure Generator (HPG) is a portable device including a pressure generating assembly and a fluid-filled chamber receiving samples for the purpose of treatment with hydrostatic pressure (Fig. 1).

HPG can be hand-operated without using any electronics and motors; simply by placing a sample in the chamber, filling the chamber with a fluid (Fig.1A); connecting the pressure generating assembly; and turning its actuator to generate pressure in the chamber (Fig.1B).

HPG can generate pressures up to at least 15-18 MPa, which is expected to be high enough to perform most of processes in an effective manner.

Potential applications, including:

- A system for facilitating fluid passage through a permeable material;

such as;

Tissue decellularization,
Bone demineralization,
Transporting nutrients/chemicals into cell seeded gels/biomaterials in tissue regeneration applications,
Extraction a compound from a material.

- A Hydrostatic Pressure Stimulation Bioreactor

such as;